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Although several explanations are considered for the observed beneficial drug effect, the fact that prednisolone therapy led to a statistically significant increase in the number of drugs prescribed, as well as the fact that prednisolone could be considered a second-line agent due to its poor efficacy in most other studies, indicates that its use is rarely recommended as first-line in the management of rheumatoid arthritis [38], [39], bm pharmaceuticals lab test.
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